GONORRHOEA - CONTEMPORARY REVIEW OF THE DISEASE AND NEW TREATMENT AGENTS


Authors: Rozalina Yordanova, Kristina Valkova
Keywords: gonorrhea, antimicrobial resistant, new treatment agents.

Abstract:
The increasing antimicrobial resistance in Neisseria gonorrhoeae observed worldwide, combined
with the increasing incidence of gonococcal infections, is a serious public health concern. Although the
disease is curable, the choice of antimicrobials used to treat gonorrhoea is very limited and cases continue
to rise internationally. The World Health Organization reports millions cases of infection each year because
of indiscriminate sexual activity, reduced condom use, increased urbanization and travel, low infection
detection rates, and inadequate or failed treatment. The purpose of this review is to provide up-to-date
information on gonorrhoea disease, antimicrobial resistance of Neisseria gonorrhoeae and the latest
treatment agents for the infection. Materials and methods: review of scientific literature, research and
international experience that provide information about gonorrhoea disease. Conclusion: Continuous
monitoring of antibiotic resistance in Neisseria gonorrhoeae and promotion of research and development
of new treatment regimens is crucial. Joint efforts between clinicians and public health professionals at the
local, national and global levels are needed to effectively prevent, identify, treat and monitor cases of
gonococcal infection, and especially those resistant to antimicrobials.
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