A HYPOTHESIS ABOUT THE FUNCTION OF NEUROMELANIN AS A BASIC INFORMATION CARRIER IN THE DEVELOPED HUMAN BRAIN (COMPL., COR.LAST)


Authors: Vasil Hadzhiiliev, Dimcho Dimov, Diana Kiselova
Keywords: human brain, neuromelanin, dihydroxyindole, postsynaptic potentials

Abstract:
The most common vision about the function of neuromelanin is correlated withits neuroprotective properties at present. But, in the last decades, there are hypotheses that its role in the human brain is more complicated and connected with a genetically controlled process of reversible transmitting and modulating the nervous impulses. We advance the hypothesis that neuromelanin plays an important role in the process of learning, especialy for the long-term memory. We propose a chemical pathway for the information accumulation in the polymeric neuromelanin molecules. This is made in dependence with the postsynaptic potentials and the properties of the neuronal enzymatic systems, especialy in the human brain.Download article